Luijsterburg lab

Transcription and DNA repair

20 May 2024

Postdoc Melanie van der Woude joins the lab on a VICI-funded project to study the role of nuclear CFAP20.

Research technician Dana Peschikova started today and will join forces with postdoc George Yakoub to study the role of DHX35 in splicing and beyond

Welcome to the team!

10 April 2023

Our collaborative paper with the labs of Julian Stingele and Steve Jackson is published in Nature Cell Biology.

Read it here

12 February 2024

Our lab symposium was great fun! Amazing science and good company

5 February 2023

Sem started as a new PhD student in the lab funded by NWO-Vici

Sem will work with George on transcription-coupled DNA repair

News

5 February 2024

Very proud to share a new paper from the lab in NSMB by Goran Kokic, George, Diana, Annelot and Paula in close collaboration with the lab of Patrick Cramer.

Read it here

24 January 2024

PhD student Sidrit Uruci contributed some very nice DNA fibers to a Molecular Cell paper from the labs of Haico van Attikum and Sylvie Noordermeer

23 January 2024

Farewell dinner with the lab for postdoc Daphne Boer who did an amazing job!

Best of luck Daphne at ProQR.

13 December 2023

Nice Christmas party with the lab

17 November 2023

Anita started as a new postdoc in the lab
in a joint position between our lab (funded by NWO) and the van der Maarel lab.

Anita will work with Annelot on a site-saturation variant screen for XPA

10 November 2023

Our Spotlight paper is out in Trends in Cell Biology. Well done George.

13 September 2023

Amazing EMBO young investigator network (YIN) meeting on Genome Integrity in Oxford with George Yakoub, Pablo Huertas, Amador Romero Franco, Miguel Ramirez and Nima Mosammaparast

16 June 2023

It was great to give a seminar at @cabimer today and discuss with the CABIMER crew. Thanks to Román González-Prieto for the kind invitation.

5 June 2023

Great speakers and lots of fun at the The ageing genome: from mechanisms to disease symposium at the EMBL in Heidelberg

1 June 2023

Postdoc Sjoerd Klaasen joins the lab on an ERC-funded project to study links between transcription and chromosome segregation.

Welcome to the team!

12 April 2023

It was a pleasure to have Orlando Schärer from IBS center for genomic integrity, Ulsan, Korea, as our guest today.

Great seminar and excellent discussions with Puck Knipscheer, Sylvie Noordermeer, Marcel Tijsterman and Diana van den Heuvel.

1 April 2023

Diana, Paula and Martijn attended the Amy & Friends retreat in the Netherlands.

It was the 10-year anniversary of the Dutch support group for Cockayne syndrome and Trichothiodystrophy.

16 March 2023

Time to celebrate three new papers from the lab published in the last three months.

Well done team and congratulations to Diana, Annelot, Paula and Katja.

10 March 2023

Very proud to share a new paper from the lab in PNAS by Diana, Annelot and Paula in close collaboration with the lab of Orlando Sharer.

We characterize a new XPA patient allele that weakens the interaction with TFIIH and selectively affects transcription-coupled nucleotide excision repair.

Read it here

This was a great team effort with contributions from former students Myrèse, Ferdy, Folkert and former lab members Katja, Angela.

1 March 2023

Postdoc Janne van Schie joins the lab on an ERC-funded project to study transcription recovery after DNA damage.

Erasmus exchange MSc student Mario López-Prieto started today and will join forces with postdoc George Yakoub to study E2 enzymes involved in TCR.

Welcome to the team!

6 February 2023

Our protocol paper describing how to perform unscheduled DNA synthesis to measure DNA repair is online in Bio-protocol.

Read it here

Congratulations to Paula and Diana. Paula’s first paper!

1 February 2023

MSc student Sem Brussee joins to the lab. He will join forces with postdoc Daphne Boer to work on establishing the dTag degradation system in the lab to deplete and study a new splicing factor.

26 January 2023

Our review on pathological consequences of DNA damage in the kidney is now online in Nature reviews in nephrology

Read it here

Thanks a lot to Juan Garaycoechea and Catherine Quinlan for writing this together.

19 January 2023

It was great to give a seminar at @imbmainz today and discuss with the IMB crew. Thanks to Helle Ulrich for the kind invitation.

12 January 2022

Excellent lab retreat today with wonderful discussions, good food and excellent company! Thank you all members of the @luijsterburglab.

15 December 2022

Our lab has two postdoc positions available at the @LUMC_Leiden to work on human DNA repair funded by @ERC_Research We are part of @EMBO_YIP

This application is closed.

14 December 2022

We had a lab X-mas party with great food, excellent company and weird presents.

27 October 2022

Lovely dinner to close off #Dutch chromatin meeting 2022 that we organized together with Haico van Attikum, John van Noort and Remus Dame.

Thanks to all the amazing speakers: Nico Thomä, Ana Pombo, Fred van Leeuwen, Sebastian Deindl, Bas Heijmans.

1 October 2022

PhD students Sidrit Uruci and Bram de Groot join the lab.

2 September 2022

What an honor and pleasure to meet transcription-coupled repair pioneer Phil Hanawalt at #ICEM2022 in Ottawa, Canada.

31 August 2022

Enjoying dinner with Mats Ljungman, Manuel Muñoz, Sofia Francia and Peng Mao after a great day at #ICEM2022 in Ottowa.

1 July 2022

PhD student Paula van der Meer and research technician Annelot Wondergem join the lab.

4 June 2022

Lovely dinner in Leiden with the lab to celebrate Katja's thesis defense and to say hello to two new PhD students. Welcome Paula and Sid.

13 April 2022

Very proud of dr. Katja Apelt who defended her doctoral thesis last month. It was a pleasure to have you in the lab. We wish you the best of luck on your new adventure at the Netherlands Patent Office.

1 April 2022

The Egmond aan Zee 2022 meeting on responses to DNA damage was amazing! The jam sessions were lots of fun! 🎤🎸🎹🎺🥁

The next meeting will be in 4 years. See you all in 2026.

17 March 2022

Very excited to share that our NWO-VICI grant was funded to study transcription-coupled DNA repair.

VENI - VIDI - VICI

A big thank you to all current and past lab members, students and our wonderful collaborators.

16 March 2022

Very excited that our ERC-Consolidator grant was funded to study transcription-coupled DNA repair and transcription-replication conflicts.

A big thank you to all current and past lab members, students and our wonderful collaborators.

10 March 2022

Great GRC meeting in Ventura, California with George-Lucian Moldovan, Marcel van Vugt and Anja Bielinsky.

17 February 2022

Congratulations to Dr. Yana van der Weegen for her cum laude dissertation defense on transcription-coupled DNA repair. Good luck at Dana-Farber Cancer Institute in Boston.

9 June 2021

Our paper in close collaboration with the lab of Rob Wolthuis describing ELOF1 as a new transcription-coupled DNA repair factor is now online in Nature Cell Biology.

https://nature.com/articles/s41556-021-00688-9

A big shout out to Yana van der Weegen, Klaas de Lint, Diana van den Heuvel and all our wonderful collaborators.